基因芯片(gene chip)

题目

基因芯片(gene chip)

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相似问题和答案

第1题:

有关基因芯片的描述,错误的是()。

A、基因芯片属于一种特殊类型的核酸杂交技术

B、基因芯片又可称为DNA微阵列

C、基因芯片制作检测的原理是DNA的半保留复制

D、基因芯片现已广泛地用于细胞或组织基因表达谱测定


答案:C

第2题:

基因芯片的应用。


答案:
解析:
(1)基因芯片是以分子微阵列和结构微阵列为基础,借助原位化学合成和芯片机械点样建成高密度探针的微阵列,芯片的固相载体支持物有硅胶片.聚丙烯膜.硝基纤维素膜三种。(3分)(2)基因芯片的应用:1)基因转录和表达图谱:基因芯片在基因表达图谱的研究中C起着重要作用。具有基因组扫措和基因功能的发现作用(适当展开)。2)单核苷酸多态性SNP:基因组内待定核背酸位置上存在两种不同的破基称为SNP。SNP通常只是一种二等位基因或二态的遗传变异。人类基因组中碱基的变异频率估计在0.5%-10%之间。3新药筛选;4)基因诊断和药物基因组学,Yershov等人利用基因芯片检测B地中海贫血患者和血细胞,发现β珠蛋白基因中存在3个突变位点。还有乳腺癌和卵巢癌等肿瘤研究的例子。另外,肿瘤相关基因组中基因转录和表达水平也会发生异常,基因芯片可以在整个基因组上扫描,确定肿瘤DNA拷贝数的变化,这为肿瘤和诊断提供了重要的信息(适当展开)。(6分)

第3题:

UP采集以()个chip为窗口,每()个chip为一个POS位置,共()组,每个位置上报一个测量结果。


本题答案:256;16;16

第4题:

CHIP不良的规格以下说法正确的是()。

  • A、CHIP短路判定NG
  • B、CHIP偏移判定OK
  • C、CHIP立碑判定NG
  • D、CHIP空焊判定NG

正确答案:A,C,D

第5题:

Chip集成电路


正确答案: 主要通称于计算机或相关产业。是把成千上万的晶体管逻辑闸如AND、OR、NOR设计浓缩在一片不到指甲大小的硅微片上,如此可缩小传统电子回路的体积。

第6题:

TD-SCDMA系统中上行导频时隙(UpPTS)的结构是()

A.GP(32chip)+SYNC(64chip)

B.GP(32chip)+SYNC(128chip)

C.SYNC(64chip)+GP(32chip)

D.SYNC(128chip)+GP(32chip)


参考答案:D

第7题:

CHIP短路的规格是:不可有。


正确答案:正确

第8题:

In July 1989, Dr.Fox and a team of scientists achieved a major scientific breakthrough.Fox discovered the gene (基因) that causes cystic fibrosis (膀胱纤维症) (CF).Many geneticists consider it 's one of the most significantdiscoveries in human genetics.Theresults of Fox work have helped scientists developtests that identify carriers of the CFgene.They hope his research could cure CF.a testhas been developed to identify peoplerrying the cystic fibrosis gene.The test isbased on knowing where the gene is locatedhe CF gene is a recessive gene.Thismeans a person can carry one copy of the gene andstill not be affected by the disease.However if this person has children with anothererson who carries the Cf genethere is a 25 chance that their children will inherit twoopies of the gene and sufferfrom the disease.The test identifies whether pat for cysticrents carrythe defective CF gene.Researchers are also using Fox discovery to find a curefibrosis.They areworking to produce a drug that will change the activity of the Cf geneId alsoattempting to replace the defective gene with one that functions properly.Itdifficultto produce a drug that changes the Cf gene but does not affect the 100000thergenes of human.But Fox discovery has at least given a chance for the cure othe CF

1.A person with ( ) of a harmful recessive gene will be affected

A.one copy

B two opies

C.no copies

D three copies.

2.We can find answers to the following questions in the passage except ()

A.Do people with CF live longer than they did in the past.

B Describeused to treat CF

C.Evaluate the current methods used to treat CF

D.Describe the drugs used to treat CF

3.The following statements are true except ()

A Only one quarter of people will have chance to have the disease.

B.Fox discovery help scientist develop tests that identify carriers of the CF gene

C.Scientist has already produced a drug to CF

D.To produce a drug is not easy because it should changes the CF gene but notaffectothers

4.The word “recessive” (line 6) probably means ()

A.hidden

B concealing

C.faint

D covered

5.The best title for the passage would be ()

A.Why People Have CF

B.The Drugs Used to Treat CF

C.The Methods of Curing CF

D.TheSignificance of the DiscoveryCystic Fibrosis Gene


参考答案:BACAD

第9题:

CHIP短路一律NG。


正确答案:正确

第10题:

何谓断裂基因(split gene)?何谓重叠基因(overlapping gene)?它们在生物进化与适应上有何意义?


正确答案:重叠基因是一段能够携带多种不同蛋白质信息的DNA片段。原核生物多含重叠基因,可以保持其基因组结构的经济性,在一定的空间范围内尽可能多的表现生命功能。
断裂基因是在DNA分子的结构基因内既含有能转录翻译的片段,也含有不转录翻译的片段。真核生物多含断裂基因,可同过对非编码区的选择性剪接产生多样性的基因表达产物以完成复杂多变的生命功能。